TLR7 and infectious disease: Among the promising TLR7 antagonists in development are compounds from the imidazo[1,2-a]pyrazine, imidazo[1,5-a]quinoxaline, and pyrazolo[1,5-a]quinoxaline series, which have been shown to be potent and selective without any TLR7/8 agonistic activity, offering potential therapeutic applications in autoimmune and infectious diseases [81].