IL5 and Alzheimer disease: AD is traditionally characterized by biphasic inflammation: Th2-inflammation is predominant in the acute phase, with the production of IL-4, IL-5, IL-13, TSLP, IL-25, and IL-31; next, a Th2-Th1 switch occurs, leading to a chronic phase (IFN-γ, IL-12, IL-5, and GM-CSF).