NLRP3 and early-onset autosomal dominant Alzheimer disease: Due to its ability to be activated by manifold types of pathogens or danger signals, NLRP3 inflammasome can play a pivotal role in various disease processes, namely, cryopyrin-associated periodic syndromes (CAPS) [37,38], Alzheimer’s disease [39], rheumatoid arthritis [40], and others [41].