Some of them are used for the treatment of diabetes mellitus (type 1 and 2) and/or obesity [11,12]: insulin detemir (Levemir®), insulin degludec (Tresiba®), liraglutide (Victoza®/Saxenda®), and semaglutide (Ozempic®, Rybelsus®, Wegovy®). The gene discussed is INS; the disease is obesity due to melanocortin 4 receptor deficiency.