The autocrine and paracrine activation of growth factors receptors in glioma cells enhances their migratory capacity, emphasizing the role of PDGFRB, EGFR and NGFR in tumor progression, and has been identified as an additional factor contributing to GBM tumor dispersal, growth, and treatment resistance [8,9,10,11,12,13]. This evidence concerns the gene NGFR and neoplasm.