In this study, we investigated ethnicity and sex-based variations in gene expression patterns, focusing on correlations between the genes PTK2, PTK2B, PDGFRB, NGFR, and CXCR1, along with a particular emphasis on EGFR, given its strong association with brain tumors, with the purpose being to elucidate the molecular underpinnings of GBM pathogenesis and address the disparities observed in different patient populations [14]. This evidence concerns the gene PTK2 and glioblastoma.