Severe COVID-19 is associated with a cytokine storm characterized by elevated plasma concentrations of interleukins (IL-1ß, IL-2, IL-6, IL-7, IL-8, IL-10 and IL-17), interferons, monocyte chemoattractant protein 1 (MCP-1) and TNF-alpha [57]. This evidence concerns the gene IL6 and COVID-19.