There were no significant differences between groups for SPARC, FGF21, IL-10, IL-15, and IL-18 serum concentrations, irrespective of the intervention status, but there was a trend towards lower circulating IL-6 levels in the T2D non-responders, although the post hoc test was not significant (p = 0.0982). This evidence concerns the gene FGF21 and type 2 diabetes mellitus.