Negative regulators of MIF and downregulated miRNAs include miRNA-451 (prostate cancer, neuroblastoma, gastric carcinoma, and hepatocellular carcinoma) [34,35,36,37], miRNA-144 and miRNA-1228 (hepatocellular carcinoma and gastric carcinoma) [37,38], and miRNA-608 (lung adenocarcinoma and glioblastoma) [39,40]. This evidence concerns the gene MIF and prostate cancer.