The grape pomace and grape polyphenols each reduced the level of ROS, oxidized glutathione (GSSG), thiobarbituric acid (TBARS) and superoxide anion (O2-) radicals, and at the same time boosted the activity of the superoxide dismutase (SOD) and catalase (CAT) enzymes, and glutathione peroxidase (GPx) and glutaredoxins (GRx) levels, revealed as the main factors in the prophylaxis of coronary diseases [169]. The gene discussed is SOD1; the disease is coronary artery disorder.