The 20 most highly expressed genes in the IDCP (cluster 10) and non-IDCP regions (Clusters 1–9) are shown in Figure 1F. Notably, MUC6, MYO16, NPY, and KLK12 emerged as highly expressed genes defining the IDCP clusters, in contrast to genes from the tumor microenvironment, such as LTF, MMP, ELN, and COL3A1, which were relatively highly expressed in the non-IDCP clusters (Figure 1H). Here, NPY is linked to neoplasm.