The results were further compared to Tsc1/Foxi1 dKO mice at 110 days of age, as shown in Figure 1F. Our results indicate that the kidney cysts were significantly smaller and less frequent in 47-day-old Tsc1/Car2 dKO mice compared to age-matched Tsc1 KO mice. This evidence concerns the gene FOXI1 and Kidney Cyst.