CYP7B1 and Familial prostate cancer: Furthermore, CYP7B1 was associated with the altered expression or activity of insulin receptors (IR-α and IR-β), along with a potential involvement in pathways related to mRNA splicing (SRSF-1); fatty acid synthesis (FAS and ACC-1); and ATPLy, CPT1a, SREBP, FAS, and PSMA expression in prostate cancer.