We examined the prognostic significance of the mRNA expression levels of the 24 genes using the UALCAN database and found that high-level expression of 10 of the genes (AMER1, BCL2A1, CCNB3, CR1, HSPA2, ITGA9, MLF1, NCX1, PDGFB, and WNT3) was associated with lower overall survival in AML patients. The gene discussed is CCNB3; the disease is acute myeloid leukemia.