JAK3 and cancer: A subset of the selected DEGs encoded proteins involved in pathways related to cancer (e.g., FAS and PIM1), chronic myeloid leukemia (e.g., AKT3 andMYC), transcriptional misregulation in cancer (e.g., RUNXT1 and BCL2A1), the regulation of endothelial cell migration (e.g., PDGFB and NOTCH1), JAK-STAT signaling (e.g., MPL and JAK3), and MAPK signaling (e.g., HSPA2 and CACNB4).