Taking together the results of the redox status of the colorectal tissue (GSH and GSSG concentrations, activity of GSH-related enzymes, activity of SOD, and TBARS concentration), it can be concluded that low-molar-mass OBG exhibits the potential to modulate the antioxidative balance in tissues altered by the early stage of CRC development, significantly diminishing the induced oxidative stress in the cancerous environment, but the effect did not depend on the doses selected in the present research. Here, GSS is linked to colorectal carcinoma.