Bartter syndrome type 4 is a disease in which both CLCNKA and CLCNKB are affected and was found to be associated with biallelic pathogenic mutations of the BSDN gene, coding for the essential Barttin subunit of both the CLCNKA and CLCNKB chloride channels [13,14]. The gene discussed is CLCNKA; the disease is Bartter syndrome type 4.