Modulating Endoplasmic Reticulum Chaperones and Mutant Protein Degradation in GABRG2(Q390X) Associated with Genetic Epilepsy with Febrile Seizures Plus and Dravet Syndrome. The gene discussed is GABRG2; the disease is encephalopathy, progressive, early-onset, with brain edema and/or leukoencephalopathy.