AHR and obesity due to melanocortin 4 receptor deficiency: This exploration encompassed various keywords and their permutations, including “cardiovascular disease”, “chronic kidney disease”, “obesity”, “fatty liver”, “metabolic syndrome”, “diabetes”, “hypertension”, “hyperlipidemia”, “pregnancy”, “gestation”, “lactation”, “progeny”, “offspring”, “mother”, “developmental programming”, “DOHaD”, “reprogramming”, “aryl hydrocarbon receptor”, “endocrine-disrupting chemicals”, “organophosphate flame retardants”, “phthalates”, “microplastics”, “heavy metals”, “air pollution”, and “PM2.5”.