Given the observed upregulation of FASN and the increased saturation of membrane lipids in CRC, both of which are linked to tumor growth and metastasis [76], and considering the essential role of de novo lipogenesis in CRC tumor growth and survival, the most straightforward approach to lower the fatty acid levels in cancer cells is through the inhibition of FASN. The gene discussed is FASN; the disease is colorectal carcinoma.