MMP2 and lung carcinoma: Genistein exerts an antimetastatic effect in the A549 lung cancer cell line by regulating the MMP-2 and PI3K/Akt pathways while playing a role in gastric cancer by inhibiting ERK1/2 and angiogenesis in ovarian cancer cells and reducing the protein levels of vascular endothelial growth factor, a potential target of ovarian cancer treatment [12,13].