As one of the hotspots in inflammatory diseases and medical oncology research in recent years, the activated NLRP3 inflammasome regulates the tumor microenvironment by controlling the secretion of Caspase~1, IL-1B, and IL-18, which induces oxidative DNA damage and uncontrolled proliferation of tissue cells, and promotes the formation and development of tumours [6]. Here, IL18 is linked to neoplasm.