CRP and obesity due to melanocortin 4 receptor deficiency: Closely related to obesity and diabetes mellitus (DM), the condition comprises a set of associated metabolic changes, such as hyperglycemia, dyslipidemia, insulin resistance, arterial hypertension, and visceral obesity, resulting in a pro-thrombotic and pro-inflammatory state accompanied by an increase in some cytokines and C-reactive protein (CRP) [4,5].