More specific antibodies for systemic sclerosis (anti-Scl70, anti-centromere, and anti-U3-RNP) were investigated in 33 of the 41 cases, and were positive only in 13 (39.4%), with anti-Scl70 the most common antibody (21.2%, 7/33). Here, RNPC3 is linked to systemic sclerosis.