With the same criteria for HF evaluation as was employed in the present study on admission (BNP ≥ 200 pg/mL or NT-proBNP ≥ 900 pg/mL), during hospitalization (clinical HF events), and at short-term follow-up (BNP ≥ 200 pg/mL or NT-proBNP ≥ 900 pg/mL), the original HFTPs predicted composite endpoints of all-cause death and HF rehospitalization [14]. The gene discussed is NPPB; the disease is hydrops fetalis.