According to these data, the ancillary human gene profiling analysis performed in a sub-cohort of our patient population also revealed that inflammation-related gene products, such as IL-1 beta, TNF-α and the anticoagulant protein (PROS1), were over-expressed in COVID-19 patients along with some viral genes (HCoV-HKU1_N, SARS-CoV2_ORF8 and SARS-CoV2_ORF7a). This evidence concerns the gene PROS1 and COVID-19.