The concentrations of cTnT and cTnI were significantly higher in the plasma of patients with severe AS as compared to healthy individuals [8.1 ng/L (5.4–17.5) vs. 0.9 ng/L (0.5–1.3) for TnI, p < 0.001; 15.2 ng/L (9.9–23.5) vs. 3.4 ng/L (3.0–5.5) for TnT, p < 0.001]. Here, TNNI3 is linked to aortic stenosis.