Moreover, the secretion of tumor chemokines such as CXCL10, CCL2, CCL3, and adhesion molecules such as ICAM-1 and VAP-1 [100] by LSECs in HCC promotes leukocytes’ recruitment and the accumulation of other immunosuppressive cells like TAMs and Tregs [101]. This evidence concerns the gene CCL3 and hepatocellular carcinoma.