Other clinical characteristics included the extent of resection (gross total (GTR), subtotal resection (STR) and biopsy), tumor location (frontal, parietal, temporal, occipital, central, and/or other or multifocal), Karnofsky performance status and preoperative epilepsy, MGMT promoter methylation status and Ki-67 status. This evidence concerns the gene MKI67 and neoplasm.