Different subtypes of HCA, such as hepatocyte-nuclear-factor-1 alpha mutated adenoma (H-HCA), inflammatory HCA (I-HCA), beta-catenin-mutated HCA (b-HCA), mixed inflammatory and beta-HCA (b-IHCA), HCA with Sonic hedgehog pathway activation (sh-HCA), and unclassified HCA (U-HCA), have been identified [117,118]. This evidence concerns the gene HNF1A and hepatocellular adenoma.