CCL20 and melanoma: Univariable Cox regression revealed that ECOG > 0 (ECOG 1 HR 4.20, 95% CI 1.95–9.07, p < 0.001; ECOG 2 HR 7.87, 95% CI 3.24–19.11, p < 0.001; ECOG 3 HR 16.14, 95% CI 5.26–49.53, p < 0.001), the high-CCL20 group (HR 1.85, 95% CI 1.02–3.37, p = 0.043) and an elevated S100 at baseline (HR 1.99, 95% CI 1.02–3.88, p = 0.043) are risk factors for decreased OS in the advanced melanoma cohort.