AKT1 and hepatocellular carcinoma: In hepatocellular carcinoma (HCC), a study by Hou et al. reported that CCL20 induces epithelial–mesenchymal transition (EMT) in HCC cell lines and activates the PI3K/AKT/mTOR pathway and the Wnt/β-catenin signaling pathway, thereby promoting proliferation and migration [15].