F2 and blood coagulation disease: Notably, higher baseline PET metabolic parameters correlated with an increased risk of coagulation disorders, evidenced by a prolonged prothrombin time and activated partial prothrombin time in the groups with a baseline MTV value ≥ 26.37 cm3, SUVmean ≥ 4.36, and TLG ≥ 78.61 [26].