TENT5C and neoplasm: Here, by describing and commenting on (1) the tumours in which the protein is actually functioning as a tumour suppressor, (2) the pathways correlated with FAM46C expression, (3) the models proposed for its mode of action, (4) how expression of FAM46C is regulated and (5) how the presence or absence of FAM46C affects cell sensitivity to anti-cancer drugs, we try to bring order to the heterogeneous literature regarding FAM46C.