M1/M2 macrophages, N1/N2 neutrophils, CD4+ T cells (T-helper), CD8+ T cells (T-cytotoxic), FOXP3+CD4+ Tregs, and antigen-presenting DCs are widely known infiltrating immune cells and are implicated in a spectrum of tumor pathologies [14,15]. The gene discussed is CD4; the disease is neoplasm.