It is clear that MMP8 or 9 mRNA expression is most significantly associated with cancer patient survival and the most significant correlation is observed in the Kidney Renal Clear Cell Carcinoma (KIRC), as shown in Fig. 7H. The clinical significance of MMP8 was further confirmed by a multivariate survival analysis in KIRC patient samples (Supplemental Table 5). Here, MMP8 is linked to cancer.