Pearson correlation analysis revealed positive correlations between gene expression in these cells (CD8 + CCL5 and ARHGAP15, p value = 0 [Fig. 5D]; TPK1 and both CD4 + FOXP3 and CD8 + ITGAE, p values = 1.6e-10 and 6.8e-08 [Fig. 5E]), further suggesting the influence of tumour cell populations on T-cell enrichment and the immune microenvironment. The gene discussed is CD8A; the disease is neoplasm.