In the 2022 WHO classification of renal cancer, in addition to TFEB amplifying renal cancer, TFEB-translocated renal cell carcinoma is included, which is a relatively rare subtype of kidney cancer typified by a translocation between the TFEB gene on chromosome 6 and the MALAT1/Alpha gene on chromosome 11 [10]. The gene discussed is TFEB; the disease is renal carcinoma.