RASGRP1 and type 1 diabetes mellitus: Recent studies have shown that multiple single nucleotide polymorphisms (SNPs) in RASGRP1 gene were related to type 2 diabetes mellitus (T2DM) [12, 13], suggesting that RASGRP1 may drive the process of T1DM through immunity, but whether it is also through a similar possible mechanism for T2DM is unclear.