To explore whether baicalin could regulate the occurrence of ferroptosis in gastric cancer through p53 or not, baicalin of 200 μM and 250 μM combined with PFN-α of 10 μM were used to treat HGC27/L cells for 24 h, and the inhibition rate of GSH, the expressions of genes p53 (Fig. 5g), SLC7A11, GPX4 (Fig. 5h), and ROS changes (Fig. 5l, m) were is needed. Here, TP53 is linked to gastric cancer.