For the hippocampus, we found a nominally significant upregulation of ESR2 (linear regression, p = 0.016 [FDR = 0.098]; Fig. S25) in female individuals with schizophrenia compared with neurotypical controls and PGR in male individuals with schizophrenia compared with neurotypical controls as a function of age (linear regression, p = 0.013 [FDR = 0.16]; Fig. S26). Here, ESR2 is linked to schizophrenia.