Likewise, NR4A3 was significantly (P < 0.05) associated with metabolic (e.g., fat-free mass), nervous/neurological (e.g., neuroticism and insomnia) and cardiovascular (e.g., resting heart rate) traits (Fig. 4e and Supplementary Data 25) and was dynamically expressed in adipose, cerebellum, heart and artery (Fig. 4d). The gene discussed is NR4A3; the disease is insomnia measurement.