APOLD1 and asthma: For instance, APOLD1, which was significantly (P < 0.05) associated with cardiovascular (e.g., high blood pressure), respiratory (e.g., asthma) and hematological (e.g., hemoglobin) traits (Fig. 4e and Supplementary Data 25), showed significant expression changes in the heart, lung and kidney (Fig. 4d).