Of note, analysis of UBC9 expression (UBE2I gene) in cell lines from CCLE revealed higher UBC9 levels in ccRCC than in TNBC cells (Fig. 1G), suggesting that in ccRCC PML may accumulate within the PML-NBs due to overexpression of its SUMO-conjugating enzyme. Here, UBE2I is linked to nonpapillary renal cell carcinoma.