As shown in Figure 5A, only the serum level of the IgG class of anti-LIMS1 autoantibody was elevated in patients with pathologic myopia (ANOVA, p < 0.0001), and no significant differences were detected in the IgM, IgA, and IgE classes among the groups (ANOVA, all p > 0.05). Here, LIMS1 is linked to myopia.