The results showed that PD-L1 expression and PD-1 checkpoint pathway in cancer (PPCPC) had a Degree of 92, Betweenness Centrality of 0.1465, and Closeness Centrality of 0.6029, thus PPCPC were predicted to be the most core signaling pathways of Danhong injection acting on IPF. Here, CD274 is linked to cancer.