As shown in Figure 7, HCC patients with high-risk score had a higher score of angiogenesis, coagulation, DNA repair, glycolysis, hypoxia, IL2_STAT5 signaling, MTORC1 signaling, and P53 pathway, indicating that the activation of these biological processes may play the vital role in HCC tumorigenesis and progression. The gene discussed is TP53; the disease is hepatocellular carcinoma.