IL6 and synovial sarcoma: Considering Kaposi’s sarcoma-associated herpesvirus (HHV-8), there is no obvious evidence that HHV-8 infection is necessarily related to SS.[42] However, HHV-8 can directly encode a kind of interleukin-6 (vll-6) and induce the expression of IL-6 in the human body, which may account for the high expression of IL-6 in some HHV-8-infected patient.[43] This suggests that HHV-8 infection may participate in SS process through its effect on IL-6.