First of all, CDCA3 exhibited elevated expression in various cancers, including gliomas, as illustrated in Figure 1A. Detailed analysis using data from the TCGA database unveiled a notably higher level of CDCA3 expression in glioblastoma (GBM) when compared to low-grade gliomas (LGG, grades 2 and 3), as depicted in Figure 1B. These findings were further substantiated by analyses of the CGGA and Rembrandt databases, as depicted in Figure 1C and D, respectively. Here, CDCA3 is linked to central nervous system cancer.