CDCA3 and glioma: First of all, CDCA3 exhibited elevated expression in various cancers, including gliomas, as illustrated in Figure 1A. Detailed analysis using data from the TCGA database unveiled a notably higher level of CDCA3 expression in glioblastoma (GBM) when compared to low-grade gliomas (LGG, grades 2 and 3), as depicted in Figure 1B. These findings were further substantiated by analyses of the CGGA and Rembrandt databases, as depicted in Figure 1C and D, respectively.