Research has shown a correlation between increased serum DGLA levels in Japanese T2D patients and factors like obesity, body fat accumulation, high ALT levels, and insulin resistance.[60] Furthermore, a study by Ju-Sheng Zheng and colleagues highlighted an increased risk of T2D associated with elevated serum DGLA concentrations.[61] However, currently, no research on the molecular mechanisms behind these findings is available. This evidence concerns the gene GPT and obesity due to melanocortin 4 receptor deficiency.