GO and KEGG enrichment analysis found that DEGs mainly enriched in “cellular divalent inorganic cation homeostasis,” “cellular zinc ion homeostasis,” “divalent inorganic cation homeostasis,” “Mineral absorption,” “Cytokine − cytokine receptor interaction,” “Coronavirus disease – COVID-19.” Two up-regulated Fe-DEGs MT1G and DDIT4 were found to further analysis. The gene discussed is DDIT4; the disease is COVID-19.