Windham et al identified that SRC could enhance the anoikis-resistant to promote the metastasis of tumor cells.[12] Moreover, it was widely reported that ARGs could predict the prognosis of some tumors including gastric cancer, breast cancer and lung cancer.[13–15] Anoikis resistance is the inherent characteristics of tumor cell,[16] but there were few reports about the function of anoikis in the PTC development. The gene discussed is SRC; the disease is neoplasm.