For instance, in pancreatic ductal adenocarcinoma cells, the Hsp90α inhibitor Octyl Gallate enhanced apoptosis, hindered endothelial-mesenchymal transition-induced M2 macrophage polarization, suppressed Hsp90α secretion, and inhibited tumor growth [26]. The gene discussed is HSP90AA1; the disease is pancreatic ductal adenocarcinoma.