In the TME, apart from tumor cells, the increased infiltration of BMDCs, such as myeloid-derived suppressor cells (MDSCs), TAMs, and tumor-associated neutrophils (TANs), mediated by various attractants, such as GM-CSF, IL-17, G-CSF, and M-CSF, lead to neovascularization and immunosuppression induction, and allow tumor cells to escape antiangiogenic therapy [333]. Here, CSF3 is linked to neoplasm.